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Displaying results 3661 - 3670 of 10000 in total
  1. Drug

    NOV-002

    go.drugbank.com/drugs/DB05393
    Investigational

    NOV-002, the lead compound acts as a chemoprotectant and an immunomodulator, in combination with chemotherapy. … NOV-002 is approved and marketed in the Russian Fereration by Pharma BAM under the trade name Glutoxim.

  2. Drug

    Palifermin

    go.drugbank.com/drugs/DB00039
    ApprovedInvestigational

    It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]

  3. Drug

    Ipragliflozin

    go.drugbank.com/drugs/DB11698
    Investigational

    Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

    Categories: Drugs Used in Diabetes
  4. Drug

    Carmofur

    go.drugbank.com/drugs/DB09010
    ApprovedWithdrawn

    Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

  5. Drug

    Androstenedione

    go.drugbank.com/drugs/DB01536
    IllicitInvestigational

    A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. … Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.

    Synonyms: Androst-4-ene-3,17-dione
  6. Drug

    2-Hydroxylpropyl-beta-cyclodextrin

    go.drugbank.com/drugs/DB15146
    Investigational

    Adrabetadex is under investigation in clinical trial NCT03887533 (Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1).

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Butylphthalide

    go.drugbank.com/drugs/DB12749
    Investigational

    Butylphthalide has been used in trials studying the prevention of Restenosis.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-n-butylphthalide, DL-3-n-butylphthalide
  8. Drug

    ATP

    go.drugbank.com/drugs/DB00171
    InvestigationalNutraceutical

    An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.

  9. Drug

    Topiroxostat

    go.drugbank.com/drugs/DB01685
    Investigational

    While [DB00437] is considered a first-line therapy in treating hyperuricemic conditions, it is often associated with side effects and ineffective in reducing uric acid levels under recommended dosing regimens … Approved for therapeutic use in Japan since 2013, topiroxostat is marketed under the name Topiloric and Uriadec and is orally administered twice daily.

  10. Drug

    XL999

    go.drugbank.com/drugs/DB05014
    Investigational

    XL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.