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Methylmethionine chloride
go.drugbank.com/drugs/DB13250ExperimentalMethylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt was determined that polaprezinc may be effective in pressure ulcer treatment [A31856]. … A study in 2013 showed that CO-administration of polaprezinc may be effective against small intestine mucosal injury associated with long-term aspirin therapy [A7840].
Aducanumab
go.drugbank.com/drugs/DB12274ApprovedInvestigational[A235720] Although aducanumab's approval represents the first drug treatment for Alzheimer's disease, the approval is conditional on further results. … [A235668,A235720] Clinical trials showed a 23% relative difference between the experimental and placebo groups as determined by CDR; however, this is equivalent to an absolute difference of 0.4/18.
Microcrystalline cellulose
go.drugbank.com/drugs/DB14158ApprovedInvestigationalAs a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Raltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalRaltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseEbvaciclib
go.drugbank.com/drugs/DB18967InvestigationalEbvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Mosliciguat
go.drugbank.com/drugs/DB19425InvestigationalMosliciguat is under investigation in clinical trial NCT06635850 (A Phase 2 Study of Mosliciguat in PH-ILD).
Ethylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalIt is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesZafirlukast
go.drugbank.com/drugs/DB00549ApprovedZafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. … Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.
Categories: Drugs for Obstructive Airway Diseases, Cytochrome P-450 SubstratesPlicamycin
go.drugbank.com/drugs/DB06810ApprovedWithdrawnPlicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus.