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Ranpirnase
go.drugbank.com/drugs/DB04950InvestigationalIt is being studied in the treatment of cancer. It is manufactured by Alfacell Corporation. It is the first ribonuclease to enter cancer clinical trials.
Mosapride
go.drugbank.com/drugs/DB11675InvestigationalMosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). … Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeInsulin-like growth factor II
go.drugbank.com/drugs/DB14472InvestigationalThe insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. … It is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults.
INZ-701
go.drugbank.com/drugs/DB17629InvestigationalINZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Synonyms: Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 (INZ-701)Leptin
go.drugbank.com/drugs/DB05098InvestigationalThese people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of insulin. … The high sustained concentrations of leptin from the enlarged fat stores result in the cells that respond to leptin becoming desensitized.
Clemastine
go.drugbank.com/drugs/DB00283ApprovedInvestigationalAn ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Boric acid
go.drugbank.com/drugs/DB11326ApprovedInvestigationalBoric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. … It is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and candidiasis [A32449].
Mixtures: TALCO MEDICADO T 24, TALCO MEDICADO T-24 LADYEthylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalIt is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. … In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeJSM 6427
go.drugbank.com/drugs/DB06139InvestigationalJSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed. … It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age of 55.
Becaplermin
go.drugbank.com/drugs/DB00102ApprovedInvestigationalBecaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae.