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Displaying results 361 - 370 of 10000 in total
  1. Drug

    Tubercidin

    go.drugbank.com/drugs/DB03172
    Experimental

    An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Sparsomycin A, 7-deazaadenosine
  2. Drug

    Pelacarsen

    go.drugbank.com/drugs/DB16284
    Investigational

    Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).

    Synonyms: AKCEA-APO(a)-LRx, IONIS-APO(a)-LRx
  3. Drug

    Formestane

    go.drugbank.com/drugs/DB08905
    ApprovedWithdrawn

    It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. … Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 4-OH-A, 4-hydroxy-4-androstene-3,17-dione
  4. Drug

    Nigericin

    go.drugbank.com/drugs/DB14056
    Experimental

    A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)

    Synonyms: Polyetherin A, Helixin CCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  5. Drug

    Zoalene

    go.drugbank.com/drugs/DB11480
    ExperimentalVet approved

    Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.

    Synonyms: Coccidine A
  6. Drug

    Aspergillopepsin-2

    go.drugbank.com/drugs/DB16571
    Investigational

    Synonyms: Proctase-A, Aspergillopepsin-2
  7. Drug

    Meningococcal polysaccharide vaccine group W-135

    go.drugbank.com/drugs/DB13887
    ApprovedInvestigational

    *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.

    Mixtures: Menomune-A/c/y/w-135, Menomune-A/c/y/w-135Synonyms: Neisseria meningitidis group W-135 polysaccharide antigen, A, Meningococcal polysaccharide antigen group W-135
  8. Drug

    Octrizole

    go.drugbank.com/drugs/DB21133
    Experimental

    Octrizole is a small molecule drug. Octrizole has a monoisotopic molecular weight of 323.2 Da.

    Synonyms: Bisoctrizole related compound a
  9. Drug

    Zopapogene imadenovec

    go.drugbank.com/drugs/DB24672
    ApprovedInvestigational

    [L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP. … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory

    Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, DNA (recombinant replication-deficient Gorilla gorilla gorilla adenovirus strain GC4 vector PRGN-2012 human cytomegalovirus promoter plus human papillomavirus 6/11 E2, E4, E6, E7 protein 11 epitope-containing
  10. Drug

    2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a

    go.drugbank.com/drugs/DB15243
    Investigational

    2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a, 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)-