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Displaying results 361 - 370 of 10000 in total
  1. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]

    Products: Propranolol HCL ER, Propranolol hcl ER
  2. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539].

    Mixtures: BENADRYL-E, BENADRYL EMSynonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamine
  3. Drug

    Darifenacin

    go.drugbank.com/drugs/DB00496
    ApprovedInvestigational

    This block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.

    Products: DARUCIL® ER 15 MG
  4. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … for an extended period.

    Mixtures: OSSICODONE E NALOXONE EG, OSSICODONE E NALOXONE EGProducts: OSSICODONE E NALOXONE EG, Xtampza ER
  5. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

    Mixtures: Osmolex ER, Osmolex ERProducts: Osmolex ER
  6. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [L33714,L33719] Naloxone was granted FDA approval on 13 April 1971.[L33709]

    Mixtures: OSSICODONE E NALOXONE EG, OSSICODONE E NALOXONE EGSynonyms: 1-N-Allyl-14-hydroxynordihydromorphinone
  7. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [A180796] The addition of two chlorine groups in the ortho position of the phenyl ring locks the ring in maximal torsion which appears to be related to increased potency. … It is often used in combination with [misoprostol] to prevent NSAID-induced gastric ulcers.

    Products: DICLOFENAC INFUSION 75MG EN SODIO CLORURO 0.7% POR 100ML, Diclofenac EC
  8. Drug

    Gefitinib

    go.drugbank.com/drugs/DB00317
    ApprovedInvestigational

    Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer.

    Synonyms: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamineProducts: GEFITINIB EG
  9. Drug

    Fluvoxamine

    go.drugbank.com/drugs/DB00176
    ApprovedInvestigational

    It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients.

    Products: FLUVOXAMINA EG, Gen-fluvoxamine 50mg
  10. Drug

    Albumin human

    go.drugbank.com/drugs/DB00062
    ApprovedInvestigational

    Also known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. … Albumin represents approximately 50% of the total protein content in healthy humans [A40060].

    Products: Pulmocis 2 mg Kit für ein radioaktives Arzneimittel, NANOTOP 0,5 mg Kit für ein radioaktives Arzneimittel