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Dimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigationaleffects are thought to be produced by 8-chlorotheophylline's adenosine receptor blockade. … [A33889] When used in large doses, dimenhydrinate has been shown to cause a "high" characterized by hallucinations, excitement, incoordination, and disorientation.
Mixtures: Arlevert 20 mg/40 mg TablettenSynonyms: (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate, O-benzhydryldimethylaminoethanol 8-chlorotheophyllinateAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalSurfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. … It stimulates synthesis and release of surfactant by type II pneumocytes.
Mixtures: AMBROXOL 150 MG / 100 ML + CLENBUTEROL 0.1 MG / 100 ML SOLUCIÓN ORAL NIÑOS, AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalIt was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil.
Products: TİGENEX 50 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 10 FLAKON, TYGEPOL 50 MG I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ, 10 ADETZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalThis compound belongs to the thioxanthenes. … It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsProducts: CLOPİXOL 10 MG FİLM KAPLI TABLET, 100 ADET, CLOPIXOL 10 MGFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is approved for use in Canada and other countries around the world, but not in the US. … [L31808] It has been marketed to manage symptoms of depression in patients who may or may not exhibit signs of anxiety.
Mixtures: DORMIR TABLET, 20 ADETCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsFerric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigationalThe latter is an iron carbohydrate oligosaccharide that works to release iron. Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January 2020. … [L11581,L11587] Clinical trials show that it is non-inferior to [iron sucrose], another form of iron that is often administered in iron deficiency, and less likely to cause serious hypersensitivity that
Products: Diafer 50 mg/ml Injektionslösung, Monofer 100 mg/ml Injektions- oder InfusionslösungPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalAlthough it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries including Canada. … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable
Mixtures: BROMUX D® 100/300 MG CÁPSULA.Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDuvakitug
go.drugbank.com/drugs/DB19444InvestigationalDuvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).
Synonyms: gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%),CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3, D12,L14 (CH1 K120 (216) (120-217), hinge 1-15 (218-Codeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.
Mixtures: A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET, GERALGINE-K 500 MG/30 MG/10 MG TABLET, 20 ADETCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XARELTO 10 MG FILM KAPLI TABLET, 100 ADET, VOXABAN 10 MG FİLM KAPLI TABLET, 100 ADET