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Displaying results 361 - 370 of 5498 in total

Drug
Zidovudine
go.drugbank.com/drugs/DB00495
ApprovedInvestigational
It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS.
Mixtures: Zidovex LN (Lamivudine 150mg, Zidovudine 300mg, Nevirapine 200mg Tablets), COMBIVIR 150MG/300MGProducts: ZIDO H ® SOLUCION ORAL 10MG/ML, ZIDOVEX 50mg/5ml (Zidovudine Oral Solution 50 mg/5ml)
Drug
Butabarbital
go.drugbank.com/drugs/DB00237
ApprovedIllicitWithdrawn
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates. This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety. Butabarbital is less common...
Products: Butisol Sodium Tab 30mg, Butisol Sodium Tab 100mg
Drug
Hydroxyzine
go.drugbank.com/drugs/DB00557
ApprovedInvestigational
[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus
Products: Atarax Cap 10mg, Multipax Cap 10mg
Drug
Pembrolizumab
go.drugbank.com/drugs/DB09037
ApprovedInvestigational
[A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Products: Keytruda 100mg Solution for Infusion, KEYTRUDA SOLUTION FOR INFUSION 25MG/ML
Drug
Estramustine
go.drugbank.com/drugs/DB01196
ApprovedWithdrawn
A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Products: Emcyt Cap 140mg, ESTRAMUSTIN UROPHARM 280MG
Drug
Nicotine
go.drugbank.com/drugs/DB00184
ApprovedInvestigational
It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Products: Nicorette Invisi Transdermal Patch 10mg/16 hours, NIQUITIN 14MG TRANSDERMAL PATCH
Drug
Trandolapril
go.drugbank.com/drugs/DB00519
ApprovedInvestigational
It is metabolized to its biologically active diacid form, trandolaprilat, in the liver.
Mixtures: TARKA 180MG/2MG, TARKA 180MG/2MGProducts: UDRIK 1MG, UDRIK 2MG
Drug
Ranitidine
go.drugbank.com/drugs/DB00863
ApprovedWithdrawn
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulc...
Products: RANITIDINA 50MG EN SODIO CLORURO 0.7 % POR 50 ML INFUSION, RANIDURA T 150MG
Drug
Naloxone
go.drugbank.com/drugs/DB01183
ApprovedInvestigationalVet approved
Notably, if injected into a person not currently using opioid medications, there would be no noticeable effects at all. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: OXYCALOXON 20MG/10MG RET, OXYCALOXON 20MG/10MG RETProducts: NALOKSON HIDROKLORUR ENJ.10AMP(D)(E, Narcan Injection 1mg/ml
Drug
Ticlopidine
go.drugbank.com/drugs/DB00208
Approved
It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they
Products: TICLOPIDIN - CT 250MG FTA, TICLOPIDINA EG