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Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39076] On the available products, ibuprofen is administered as a racemic mixture. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.
Mixtures: MAXIFEN D, MAXIFEN DProducts: TISPOL IBU DD, Dg Health IbuprofenChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.
Mixtures: Actidom Da, Dometuss-DAProducts: CLOROTRIMETON DE 8 MGTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalMechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities.
Mixtures: I D M Expectorant Tab, TUSBRON-A JARABECategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.
International brands: Shuang DiProducts: COLYPAN ®300 MG TABLETAS DE LIBERACION PROLONGADA, TRIMEBUTINA MALEATO 300 MG TABLETA DE LIBERACIÓN PROLONGADATriclocarban
go.drugbank.com/drugs/DB11155ApprovedIt is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal
Products: DG Body Antibacterial Deodorant 3.5 oz barTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma. … Both the European Commission and the U.S. Food and Drug Administration (FDA) have approved trabectedin as an orphan drug in soft tissue sarcomas and ovarian cancer.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexCyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedCyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. … [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Synonyms: Cyclosporin A, Cyclosporine ACategories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedPharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].
Products: N/A, GESTAGENO®100MG CÁPSULAS DE GELATINA BLANDAMeclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigationalMeclizine is a histamine H1 antagonist with antiemetic and antivertigo properties.
Products: Motion Sickness All Day Less Drowsy