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Displaying results 3701 - 3710 of 10000 in total
  1. Drug

    Veglin

    go.drugbank.com/drugs/DB05890
    Experimental

    VEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma … Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization in the ongoing struggle to combat malignant mesothelioma.

  2. Drug

    Zavacorilant

    go.drugbank.com/drugs/DB21509
    Investigational

    The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal). … Zavacorilant has a monoisotopic molecular weight of 555.15 Da.

  3. Drug

    Paliroden

    go.drugbank.com/drugs/DB05454
    Investigational

    Paliroden is an orally active neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines.

  4. Drug

    Alfacalcidol

    go.drugbank.com/drugs/DB01436
    ApprovedInvestigationalNutraceutical

    Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones.

    Synonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diol
  5. Drug

    Hydroxyamphetamine

    go.drugbank.com/drugs/DB09352
    Approved

    The main use of hydroxyamphetamines as eye drops is the diagnosis of Horner's syndrome which is characterized by nerve lesions. … Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and temporary

  6. Drug

    3,4-Methylenedioxy-N-isopropylamphetamine

    go.drugbank.com/drugs/DB06112
    Experimental

    MDI-P has demonstrated potent anti-HIV activity. MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). MDI-P is also a potential therapeutic agent fo...

    Synonyms: 3,4-Methylenedioxy-N-isopropylamphetamine
  7. Drug

    NS-398

    go.drugbank.com/drugs/DB14060
    Experimental

    NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.

    Synonyms: N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamideCategories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal
  8. Drug

    Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

    go.drugbank.com/drugs/DB16443
    Investigational

    In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection[A226853]. … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853].

  9. Drug

    Mitapivat

    go.drugbank.com/drugs/DB16236
    ApprovedInvestigational

    Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various ...

  10. Drug

    Apramycin

    go.drugbank.com/drugs/DB04626
    InvestigationalVet approved

    It is not approved for use in humans.