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Displaying results 3711 - 3720 of 10000 in total
  1. Drug

    Enmetazobactam

    go.drugbank.com/drugs/DB18716
    ApprovedInvestigational

    Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. … [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections.

  2. Drug

    XP21279

    go.drugbank.com/drugs/DB06319
    Investigational

    XP21279 is a prodrug of [Levodopa], a dopamine precursor used in the management of Parkinson's disease.

  3. Drug

    Tritoqualine

    go.drugbank.com/drugs/DB13711
    Approved

    Categories: Antihistamines for Systemic Use
  4. Drug

    CYT-6091

    go.drugbank.com/drugs/DB05991
    Experimental

    It was under investagtion in clinical trials NCT00356980 and NCT00436410 for the treatment of various cancers.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    99mTc-glucarate

    go.drugbank.com/drugs/DB05810
    Investigational

    99mTc-glucarate(GLA) is an agent for non-invasive detection of breast tumours.

  6. Drug

    Proparacaine

    go.drugbank.com/drugs/DB00807
    ApprovedVet approved

    Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.

  7. Drug

    1,2-Hexanediol

    go.drugbank.com/drugs/DB14108
    Investigational

    Mixtures: Anbiser B-HA HYALURONIC ACID MOISTURIZING
  8. Drug

    GTI-2501

    go.drugbank.com/drugs/DB05406
    Experimental

    The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. … GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial.

  9. Drug

    Plozasiran

    go.drugbank.com/drugs/DB18997
    ApprovedInvestigational

    Plozasiran (ARO-APOC3) is a small interfering RNA (siRNA) that degrades apolipoprotein C-III (apoC-III) mRNA by RNA interference. … Plozasiran contains a covalently linked ligand containing three N-acetylgalactosamine (GalNAc) residues to facilitate delivery to hepatocytes where it works to reduce triglyceride levels.

  10. Drug

    DTS-201

    go.drugbank.com/drugs/DB06071
    Experimental

    DTS-201 is a prodrug of doxorubicin, a widely used anti-cancer drug that Diatos intends to develop for the treatment of various solid tumors. It is activated in the tumor environment. … express high levels of CD-10* or TOP** peptidases, such as prostate cancer, colorectal cancer, melanoma, pancreatic cancer and some types of renal cancer.