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SP1049C
go.drugbank.com/drugs/DB04978ExperimentalPreliminary data, in its first clinically tested indication, shows that SP1049C is active in Stage IV non-resectable adenocarcinoma of the esophagus. … [A260416] It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review.
Categories: Compounds used in a research, industrial, or household settingMetharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnIt was patented in 1905 by Emil Fischer of Merck.
Spaglumic acid
go.drugbank.com/drugs/DB08835InvestigationalSpaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). … Specifically spaglumic acid is approved in Portugal under the brand name Naabak and in Greece under the brand name Naaxia for use in patients with allergic conjunctivitis.
Synonyms: N-Acetyl-L-β-aspartyl-L-glutamic acidTienilic acid
go.drugbank.com/drugs/DB04831ApprovedWithdrawnIt was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Phenyl salicylate
go.drugbank.com/drugs/DB11071ApprovedIt is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in [DB00945] ). … It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes.
Mixtures: UR N-C Urinary Antiseptic2-Hydroxylpropyl-beta-cyclodextrin
go.drugbank.com/drugs/DB15146InvestigationalAdrabetadex is under investigation in clinical trial NCT03887533 (Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1).
Categories: Compounds used in a research, industrial, or household settingPhosmet
go.drugbank.com/drugs/DB11448ExperimentalVet approvedIt is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.
Categories: Compounds used in a research, industrial, or household settingXimelagatran
go.drugbank.com/drugs/DB04898ApprovedWithdrawnIn 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.
Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetateCamostat
go.drugbank.com/drugs/DB13729Investigational[A193842,A193848] It was first described in the literature in 1981, as part of research on the inhibition of skin tumors in mice. … [A198771,A198777,A193800] Camostat mesylate was first approved in Japan in January 2006.[L13197]
ATP
go.drugbank.com/drugs/DB00171InvestigationalNutraceuticalAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.