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Naftidrofuryl
go.drugbank.com/drugs/DB13588ApprovedCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: PRAXILENE TABLET 200 mg, Dusodril retard 100 mg - FilmtablettenReboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. … Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Edronax 4 mg - Tabletten, EDRONAX 4 MG TABLET, 60 ADETTrastuzumab deruxtecan
go.drugbank.com/drugs/DB14962ApprovedInvestigationalTrastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. … [A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and was first approved by the FDA in 2019.[L10842]
Categories: MATE 2 Substrates, HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsSynonyms: T-DXd, T- DXdNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. … Neratinib is currently under investigation for use in many other forms of cancer.
Categories: Heterocyclic Compounds, 2-Ring, Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitorsSynonyms: 奈拉替尼Choline salicylate
go.drugbank.com/drugs/DB14006ApprovedNutraceuticalThis drug is also a main ingredient in teething gels to relieve pains associated with tooth growth in the infant population [L2134]. … The UK government has regulated its use, due to toxicity in those under 16 years of age.
Products: DENCOL JEL SPREY, 20 G, Colident %8.71 jel sprey, 20 GLenvatinib
go.drugbank.com/drugs/DB09078ApprovedInvestigationalMost patients with thyroid cancer have a very good prognosis with treatment (98% 5 year survival rate) involving surgery and hormone therapy. … factor (FGF) receptors FGFR1, 2, 3, and 4; the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamideIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalIt is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026]. … has a potential for nephrotoxicity [A32029].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 InducersProducts: CRESEMBA (100 MG HARD CAPSULES), CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL)Glycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose, Amino Acid InJ.W.elecw.25%dexProducts: GLICINA IRRIGACION 1.5% M/V, GLICINA IRRIGACION USP (1.5% W/V)BOLSA POR 3000 MLIndinavir
go.drugbank.com/drugs/DB00224ApprovedInvestigationalA potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsSynonyms: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamideSulfacetamide
go.drugbank.com/drugs/DB00634ApprovedAn anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Mixtures: BRUMETON 1 MG/ML+100 MG/ML GÖZ DAMLASI, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLSynonyms: N(1)-Acetylsulfanilamide, N(1)-Acetyl-4-aminophenylsulfonamide