Search
Cobimetinib
go.drugbank.com/drugs/DB05239ApprovedInvestigationalCobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction … It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma.
Categories: Heterocyclic Compounds, 1-Ring, MAP Kinase Kinase 1, antagonists & inhibitorsProducts: COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTAS, COTELLIC FILM-COATED TABLET 20 MGPivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalIt is active against gram-negative organisms and used as for amdinocillin. [PubChem] … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Categories: Heterocyclic Compounds, 2-RingProducts: Selexid 200 mg Filmtabletten, Selexid 400 mg film-coated tabletsDe Novo Triacylglycerol Biosynthesis TG(10:0/10:0/10:0)
smpdb.ca/view/SMP0015899MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/12:0)
smpdb.ca/view/SMP0175276MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/14:0)
smpdb.ca/view/SMP0175278MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/22:0)
smpdb.ca/view/SMP0175287MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(8:0/10:0/10:0/10:0)
smpdb.ca/view/SMP0226114MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Enfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigational[L10836] It is similar to [brentuximab vedotin], another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4. … [L10836] It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PADCEV 20 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADET, PADCEV 30 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADETSertaconazole
go.drugbank.com/drugs/DB01153ApprovedIt is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Heterocyclic Compounds, 1-RingProducts: ZALAIN 300 MG VAJINAL SUPOZITUVAR, 1 ADET, ZALAIN VAGINAL SUPPOSITORY 300 mgPizotifen
go.drugbank.com/drugs/DB06153Approved[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AntagonistsProducts: SANDOMIGRAN 0,5 MG KAPLI TABLET, 30 ADET, Pizogran Tablet 0.5 mg