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Displaying results 3741 - 3750 of 10000 in total
  1. Drug

    Rifapentine

    go.drugbank.com/drugs/DB01201
    ApprovedInvestigational

    Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. … Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

  2. Drug

    Ancrod

    go.drugbank.com/drugs/DB05099
    ApprovedWithdrawn

    Currently, Viprinex®/ancrod is not approved or marketed in any country, but is being investigated as a stroke treatment in worldwide clinical trials. In January 2005, the U.S. … Ancrod, marketed as Viprinex, is a defibrinogenating agent derived from Malayan pit viper venom. The defribrinogenation of blood results in an anticoagulant effect.

  3. Drug

    Pradefovir mesylate

    go.drugbank.com/drugs/DB05478
    Investigational

    Pradefovir is activated through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver. … The novel prodrug is highly stable in both plasma and tissues and demonstrated potent preclinical and clinical anti-HBV activity.

  4. Drug

    Arbaclofen Placarbil

    go.drugbank.com/drugs/DB08892
    Investigational

    by XenoPort in 2011 for the treatment of GERD. … Arbaclofen Placerbil was believed to have therapeutic potential in treating gastroesophogeal reflux disease (GERD) and plasticity; however due to discouraging clinical trial results, the drug was abandoned

  5. Drug

    Gusperimus

    go.drugbank.com/drugs/DB12692
    Investigational

    Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.

  7. Drug

    Trimethyltetradecylammonium

    go.drugbank.com/drugs/DB17342
    Experimental

    Synonyms: Tetradonium ion, 1-tetradecanaminium, n,n,n-trimethyl-Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    3,4-Dihydroxycinnamic Acid

    go.drugbank.com/drugs/DB01880
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Aminoethyl nitrate

    go.drugbank.com/drugs/DB13585
    Experimental

    Categories: Vasodilators Used in Cardiac Diseases
  10. Drug

    Sonlicromanol

    go.drugbank.com/drugs/DB16333
    Investigational

    Sonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-Carboxamide