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Zilovertamab vedotin
go.drugbank.com/drugs/DB18457InvestigationalZilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (
Prinaberel
go.drugbank.com/drugs/DB06832InvestigationalPrinaberel is an estrogen receptor beta agonist.
NN-8828
go.drugbank.com/drugs/DB18361InvestigationalNN-8828 is an anti-interleukin 21 monoclonal antibody.
AVE9633
go.drugbank.com/drugs/DB06318InvestigationalAVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsEtynodiol
go.drugbank.com/drugs/DB13866ExperimentalEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesChlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawn[L43942,L42975] Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and tolerability.[A254422,L33974]
Resmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigationalOn March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsNitarsone
go.drugbank.com/drugs/DB11437ExperimentalVet approvedNitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease.
Synonyms: (p-nitrophenyl)arsonic acid, p-nitrophenylarsonic acidThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigationalThyroid extract is dried and powdered thyroid glands from pigs containing tiiodothyronine (T3) and thyroxine (T4) used to supplement low or absent thyroid activity. Thyroid extract has been described in literature to treat hypothyroidism...
Pentagastrin
go.drugbank.com/drugs/DB00183ApprovedA synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.