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Disintegrin and metalloproteinase domain-containing protein 10
go.drugbank.com/bio_entities/BE0002404TargetHumansTransmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis (PubMe...
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 10Synonyms: ADAM 10Sialic acid-binding Ig-like lectin 10
go.drugbank.com/bio_entities/BE0018431TargetHumansPutative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with ...
Polypeptides: Sialic acid-binding Ig-like lectin 10Synonyms: Siglec-10Nilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: Tensan retard 8 mg - Kapseln, ESCOR FORTE 16MG RET KAPCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnIt was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. … Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Carbomer 974 (P), Carbomer homopolymer type BDiatrizoate
go.drugbank.com/drugs/DB00271ApprovedVet approvedA commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Mixtures: UROGRAFIN %76 IV ENJEKSIYON VE INFUZYON ICIN COZELTI, 50 ML, Md-60Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedPipenzolate
go.drugbank.com/drugs/DB13844InvestigationalMixtures: LIBKOL FILM TABLET, 50 ADET, LIBKOL FILM TABLET, 20 TABLETCategories: Heterocyclic Compounds, 1-RingPraziquantel
go.drugbank.com/drugs/DB01058ApprovedInvestigationalVet approvedSpecifically, it is known as a treatment of trematodes and cestodes infections such as schistosomiasis, taeniasis, and cysticercosis. … [A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: DISTOCIDE TABLET 600 mg, CISTICID ® 600MGAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1, (115-212), hinge 1-12 S10>P (222) (213-224), CH2 LDapoxetine
go.drugbank.com/drugs/DB04884InvestigationalIn October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions. … In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.
Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsCardiolipin Biosynthesis CL(10:0/10:0/10:0/20:0)
smpdb.ca/view/SMP0175285MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.