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Displaying results 3741 - 3750 of 10000 in total
  1. Drug

    Aprepitant

    go.drugbank.com/drugs/DB00673
    ApprovedInvestigational

    Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.

    Mixtures: LEMID® 125/80, LEMID® 125/80Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists
  2. Drug

    Imetelstat

    go.drugbank.com/drugs/DB14909
    ApprovedInvestigational

    Imetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase. … [A263973] It is used to treat anemia in patients with myelodysplastic syndromes (MDS), a group of hematologic disorders characterized by ineffective hematopoiesis, peripheral cytopenia, abnormal marrow

  3. Drug

    Diphemanil

    go.drugbank.com/drugs/DB13720
    ApprovedVet approvedWithdrawn

    Synonyms: Diphemanil ionCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Drotaverine

    go.drugbank.com/drugs/DB06751
    ApprovedWithdrawn

    Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … [A231619] It is a benzylisoquinoline derivative that is structurally related to [papaverine], although it displays more potent antispasmodic activities than papaverine.

    Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 Inhibitors
  5. Drug

    Nicergoline

    go.drugbank.com/drugs/DB00699
    Approved

    An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.

    Synonyms: (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester), 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinateCategories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor Antagonists
  6. Drug

    Albumin Aggregated

    go.drugbank.com/drugs/DB14230
    Approved

    Albumin aggregated is an ingredient in the DRAXIMAGE MAA kit for the preparation of technetium tc99m albumin aggregated injection. … [L12816] This imaging agent is used to assess lung perfusion and for the evaluation of peritoneovenous (LeVeen) shunt patency.

  7. Drug

    N-(2-Aminoethyl)-1-aziridineethanamine

    go.drugbank.com/drugs/DB15643
    Experimental

    First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease

    Synonyms: N-(2-((2-Aminoethyl)amino)ethyl)aziridine, N-(2-aminoethyl)-1 aziridine-ethanamineCategories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Acebutolol

    go.drugbank.com/drugs/DB01193
    ApprovedInvestigational

    A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.

    Synonyms: N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamideCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Ecabet

    go.drugbank.com/drugs/DB05265
    Investigational

    Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis. … Ecabet is a prescription eye drop for the treatment of dry eye syndrome.

    Categories: Compounds used in a research, industrial, or household setting, Pepsin A, antagonists & inhibitors
  10. Drug

    p-Phenylenediamine

    go.drugbank.com/drugs/DB14141
    Approved

    Synonyms: 4-Aminoaniline, p-DiaminobenzeneSalts: p-Phenylenediamine dihydrochloride