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Ixmyelocel-T

Ixmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.

Utidelone

Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.

mRNA-3705

mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]

ETC-588

It is believed that the removal of cholesterol by ETC-588 through this pathway may result in the reversal of atherosclerosis.

Mazindol

Mazindol is a tricyclic anorexigenic agent that is unrelated to and less toxic than [amphetamine], but with some similar side effects.

Inositol nicotinate

It is associated with reduced flushing compared to other vasodilators by being broken down into the metabolites and inositol at a slower rate. … Nicotinic acid plays an essential role in many important metabolic processes and has been used as lipid-lowering agent.

BBM-H803

BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed. … It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.

Hu-rhEGF-rP64k/Mont

Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated

GnRH pharmaccine

The pharmaccine is administered intramuscularly to the patient by injection and induces an immune response or production of antibodies in the patient, which neutralize GnRH thus removing it from circulation

Caldaret