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Displaying results 3761 - 3770 of 10000 in total
  1. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. … Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication.

  2. Drug

    Xanomeline

    go.drugbank.com/drugs/DB15357
    ApprovedInvestigational

    [A264514] Xanomeline is a muscarinic agonist that was approved for the treatment of schizophrenia by the FDA in September 2024, becoming the first approved treatment for schizophrenia to target muscarinic … Schizophrenia is a complex disease involving a number of different neurotransmitters, including serotonin, dopamine, and acetylcholine.

  3. Drug

    Barnidipine

    go.drugbank.com/drugs/DB09227
    Investigational

    Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall [L1131] and selectivity against cardiovascular L-type … Compared to several other calcium antagonists which are racemates, the barnidipine compound consisting of a single enantiomer may offer a high degree of pharmacological selectivity [A31567].

  4. Drug

    Tedisamil

    go.drugbank.com/drugs/DB06200
    Experimental

    Tedisamil (planned trade name Pulzium) is an investigational drug for atrial fibrillation and atrial flutter.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Actinium Ac 225 Vipivotide tetraxetan

    go.drugbank.com/drugs/DB23637
    Investigational

    Actinium Ac 225 Vipivotide Tetraxetan is a small molecule drug. … for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma).

  6. Drug

    Anileridine

    go.drugbank.com/drugs/DB00913
    ApprovedIllicitWithdrawn

    Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain.

  7. Drug

    2-Hydroxylpropyl-beta-cyclodextrin

    go.drugbank.com/drugs/DB15146
    Investigational

    Adrabetadex is under investigation in clinical trial NCT03887533 (Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1).

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Strontium chloride Sr-89

    go.drugbank.com/drugs/DB09498
    Approved

    [A31264] Bone metastases is a common and severe complication presented in advanced stages of the disease. … There has been some cases of apparent tumor regression which has given it a potential tumoricidal effect.[A31263]

  9. Drug

    Ferric carboxymaltose

    go.drugbank.com/drugs/DB08917
    ApprovedInvestigational

    Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.

    Categories: Compounds used in a research, industrial, or household settingProducts: Ferinject Solution for Injection 50mg/ml, Ferinject® 50 mg iron/mL solution for injection/infusion
  10. Drug

    Dicoumarol

    go.drugbank.com/drugs/DB00266
    Approved

    Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index