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Chymotrypsin

Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice.

Biguanide

Biguanide has been investigated for the treatment of Diabetes Mellitus.

Iberdomide

[L64055,L64056] It is the first cereblon E3 ligase modulator (CELMoD) approved for multiple myeloma.[L64057] … at least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent.

Ravidasvir

Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).

Vinpocetine

Vinpocetine has been investigated for the treatment of Epilepsy.

Coblopasvir

Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).

MAS825

Tirapazamine

This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia. … Tirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological cancer, as well as for other solid tumor cancer types.

Buformin

It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis. … Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin.

Eniluracil

the U.S. and is often first or second line therapy for a variety of cancers including colorectal, breast, gastric, head and neck, ovarian and basal cell cancer of the skin. … Eniluracil has received Orphan Drug status from the FDA for the treatment of hepatocellular cancer in combination with fluoropyrimidines (including 5-FU).