Buformin

DB04830ApprovedWithdrawnSmall molecule

Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of...

Formula / weight: C₆H₁₅N₅ · 157.2168 g/mol (avg)
Also known as: 1-Butylbiguanide
Code names: W-37

Resolves to

Compound

UNIIW2115E9C7BCAS692-13-7ChEMBLCHEMBL39736ChEBI3209PubChem2468KEGGD00595

Clinical / RWD

ATCA10BA03

Structure

InChIKeyXSEUMFJMFFMCIU-UHFFFAOYSA-NSMILESCCCC\N=C(/N)N=C(N)N

Transporters

Q9H015SLC22A4O15245SLC22A1

What you can answer from here — as of August 30, 2026

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

646Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

1ATC codeIncluding every combination product, plus 8 drug categories

5+ReferencesStructured and connected to the statements they support

Which companies are running trials of Buformin, in which indications and phases, and which of those programs are still active?

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