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PF-03187207

The development of abnormally high IOP, due to blockage or malfunction of systems controlling the amount of fluid in the eye, is believed to be one of the principal causes of glaucoma. … Based on the very promising preclinical results and on the well-known activities of nitric oxide, PF-03187207 is expected to have an increased capacity to reduce high IOP.

Pyrvinium

Pyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under inves...

o-Cymen-5-ol

Bambusa arundinacea stem

Maltodextrin

Picoplatin

It causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription. … Picoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with solid tumors.

SRP 299

A specific subset of serotonergic neurons in the interfascicular part of the dorsal raphe nucleus (DRI) is believed to be involved, based on studies with mice. … Mycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of regulatory T-cells that surpress inappropriate Th2

Pentosan polysulfate

Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.

VP025

It also shows the ability to reduce inflammation across the blood-brain barrier and improve correlates of memory and learning function. … It is considered to be a systemic anti-inflammatory and neuroprotective agent.

XL765

XL765 is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR).