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Glucagon
go.drugbank.com/drugs/DB00040ApprovedInvestigationalGlucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. … [L7640,L7643] Glucagon was granted FDA approval on 14 November 1960.[L7631]
Pinacidil
go.drugbank.com/drugs/DB06762ApprovedThe above processes result in reduced blood pressure. This drug has been discontinued by the FDA. … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance.
Categories: Arteriolar Smooth Muscle, Agents Acting OnAcrihellin
go.drugbank.com/drugs/DB21069ExperimentalAcrihellin is a small molecule drug. Acrihellin has a monoisotopic molecular weight of 498.26 Da.
Categories: Compounds used in a research, industrial, or household settingZinc picolinate
go.drugbank.com/drugs/DB11175InvestigationalZinc picolinate is a zinc salt of picolinic acid. It is available as OTC dietary supplements as a source of zinc to treat and prevent zinc deficiency. … The absorption of zinc after oral administration of zinc picolinate is shown to be effective.
Categories: Compounds used in a research, industrial, or household settingCiluprevir
go.drugbank.com/drugs/DB05868InvestigationalThe compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
CX-046684
go.drugbank.com/drugs/DB19414ApprovedIt is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.[L40074] … CX-046684 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage KP.2.
Glutaral
go.drugbank.com/drugs/DB03266InvestigationalOne of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Categories: Compounds used in a research, industrial, or household settingSulfadiazine
go.drugbank.com/drugs/DB00359ApprovedInvestigationalVet approvedOne of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Synonyms: N(1)-2-Pyrimidylsulfanilamide, N(1)-2-PyrimidinylsulfanilamideSNS-314
go.drugbank.com/drugs/DB06134InvestigationalSNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single agent Phase 1 studies in patients with advanced solid tumours. … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C.
Sonlicromanol
go.drugbank.com/drugs/DB16333InvestigationalSonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Synonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideCategories: Compounds used in a research, industrial, or household setting