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Displaying results 371 - 380 of 10000 in total
  1. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Hunter syndrome is a rare, X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), which leads to the toxic accumulation of glycosaminoglycans (GAGs) throughout … Tividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099

    Synonyms: - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T, 676>S, L 678>A, Y
  2. Drug

    Stallimycin

    go.drugbank.com/drugs/DB20261
    Experimental

    Stallimycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Stallimycin is a antibiotic, produced by Streptomyces strain. … Stallimycin has a monoisotopic molecular weight of 481.22 Da.

    Synonyms: Distamycin a
  3. Drug

    Basifungin

    go.drugbank.com/drugs/DB14058
    Experimental

    Basifungin, also known as _aureuobacidin A_, is a phosphorylceramide synthase inhibitor [L2960], [A33381].

    Synonyms: Aureobasidin A
  4. Drug

    Streptolydigin

    go.drugbank.com/drugs/DB04785
    Experimental

    Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

    Synonyms: Afragilimycin A
  5. Drug

    Hexanoyl-CoA

    go.drugbank.com/drugs/DB02563
    Experimental

    Synonyms: n-hexanoyl-coenzyme A, S-Hexanoyl-coenzym-ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  6. Drug

    Acetoacetyl-CoA

    go.drugbank.com/drugs/DB03059
    Experimental

    Synonyms: S-Acetoacetyl-coenzym A, S-acetoacetyl-coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  7. Drug

    Novobiocin

    go.drugbank.com/drugs/DB01051
    ApprovedInvestigationalVet approvedWithdrawn

    Novobiocin is an antibiotic compound derived from _Streptomyces niveus_. It has a chemical structure similar to coumarin. … (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious

    Synonyms: N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE

    go.drugbank.com/drugs/DB04677
    Experimental

    Synonyms: N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE
  9. Drug

    Lixadesiran

    go.drugbank.com/drugs/DB17295
    Experimental

    Synonyms: Rna, (a-c-a-u-c-a-u-c-a-g-a-c-c-a-g-g-c-a-c-c-a-g-a-c-c), complex with rna (g-g-u-c-u-g-g-u-g-c-c-u-g-g-u-c-u-g-a-u-g-a-u-g-u) (1:1)
  10. Drug

    Malonyl-CoA

    go.drugbank.com/drugs/DB04524
    Experimental

    A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.

    Synonyms: Malonyl coenzyme A, S-(Hydrogen malonyl)coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring