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Sitaxentan
go.drugbank.com/drugs/DB06268ApprovedWithdrawnIn 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Loperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976.
Products: LOPERAMIDE EG, Rx Act Anti DiarrhealMagnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigationalMagnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium in...
Mixtures: Revit Multi-vitamins and Minerals, C-Nate DHAProducts: EMGE 300MG PULV Z.HER E LOSodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: E-Z-gas II, MACROGOL EGProducts: BICARBONATO DE SODIO EN POLVO - 45, After Bite X Techalpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approvedMost individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
Mixtures: Revit Plus Cap, Revit Multi-vitamins and MineralsCategories: Vitamin EPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalPioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. It is administered as a racemic mixture, though there is no pharmacologic difference betwee...
Mixtures: PIOGLITAZONE E METFORMINA EG, PIOGLITAZONE E METFORMINA EGProducts: PIOGLITAZONE EGEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
International brands: ES-ODProducts: E-SOME, ESOMEPRAZOLO EGTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. ...
Products: ACIDO TRANEXAMICO EGLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affe...
Products: LETROZOLO EGBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnThe use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.