Magnesium is a medication used for many purposes including constipation, indigestion, magnesium deficiency, and pre-eclampsia. Magnesium is classified as an alkaline earth metal and has 2 hydration shells.
- Mechanism
- Curator reviewed · 6 references
Magnesium is a cofactor for at least 300 enzymes and is important for several functions in the body with some key processes identified below. Enzymes that rely on magnesium to operate help produce energy through oxidative phosphorylation, glycolysis and ATP metabolism. They are also involved in nerve function, muscle contraction, blood glucose control, hormone receptor binding, protein synthesis, cardiac excitability, blood pressure control, gating of calcium channels and transmembrane ion flux.
The mitochondrial intracellular space is rich in magnesium, since it is required to produce the active form of ATP (adenosine triphosphate) from ADP (adenosine diphosphate) and inorganic phosphate, and behaves as a counter ion for the energy rich molecule. Additionally, magnesium is essential for ATP metabolism.
- Primary indication
- Healthy levels of magnesium can be achieved through a well balanced diet, but if food sources are insufficient, magnesium supplements can be used to prevent and treat magnesium deficiencies.Curator reviewed · 7 structured indications
- Formula / weight
- H2Mg · 26.321 g/mol (avg)
- First approval
- Canada, 1996 · United States, 2015
- Also known as
- Magnesium metallicum · Magnesium powder
- Brand names
Resolves to
RSHAOIXHUHAZPM-UHFFFAOYSA-NSMILES[MgH2]What you can answer from here — as of October 06, 2025
Which other approved drugs treat the same conditions as Magnesium, and which companies have late-stage candidates in those indications?
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