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Evalstotug
go.drugbank.com/drugs/DB19410InvestigationalEvalstotug is under investigation in clinical trial NCT05271604 (A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck).
Synonyms: Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], monoclonal antibody, Immunoglobulin G1 [de-448-lysine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal BA3071 γ1-chain), disulfide with human monoclonal BA3071 κ-chain, dimerBremzalerbart
go.drugbank.com/drugs/DB19417InvestigationalBremzalerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Synonyms: immunoglobulin G4-kappa, anti-[Bet v 1 (Betula alleghaniensis (yellow birch) pollen allergen 1)], Homo sapiens monoclonal antibody, gamma4 heavy chain Homo sapiens (1-443) [VH (Homo sapiens IGHV4-59*01, Immunoglobulin G4 [224-proline], anti-(Betula alleghaniensis allergen Bet v 1) (human monoclonal REGN5713 γ4-chain), disulfide with human monoclonal REGN5713 κ-chain, dimerAtisnolerbart
go.drugbank.com/drugs/DB19418InvestigationalAtisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Synonyms: L92 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230),, gamma4 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV1-8*03 (86.7%) -(IGHD) - IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51- 58.97-109)) (1-120)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2Duvakitug
go.drugbank.com/drugs/DB19444InvestigationalDuvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).
Synonyms: gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%),CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3, D12,L14 (CH1 K120 (216) (120-217), hinge 1-15 (218-Epertinib
go.drugbank.com/drugs/DB20062ExperimentalEpertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Epertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Epertinib has a monoisotopic molecular weight of 559.18 Da.
Categories: Heterocyclic Compounds, 2-RingRifamexil
go.drugbank.com/drugs/DB20067ExperimentalRifamexil is a small molecule drug. Rifamexil has a monoisotopic molecular weight of 809.36 Da.
Categories: Heterocyclic Compounds with 4 or More RingsValactate
go.drugbank.com/drugs/DB20086ExperimentalValactate is a small molecule drug. Valactate has a monoisotopic molecular weight of 188.09 Da.
Lapretolimod
go.drugbank.com/drugs/DB20120InvestigationalLapretolimod is under investigation in clinical trial NCT03799510 (Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children). Lapretolimod has a monoisotopic molecular weight of 1745.28 Da. … Lapretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Lapretolimod is a toll-like receptor (TLR) agonist.
Synonyms: Glucopyranosyl lipid aFasobegron
go.drugbank.com/drugs/DB20200ExperimentalFasobegron is a small molecule drug. The usage of the INN stem '-begron' in the name indicates that Fasobegron is a β3 adrenoreceptor agonists. … Fasobegron has a monoisotopic molecular weight of 425.14 Da.
Azamulin
go.drugbank.com/drugs/DB20304ExperimentalAzamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates