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Displaying results 3821 - 3830 of 10000 in total
  1. Drug

    Stapokibart

    go.drugbank.com/drugs/DB18990
    Investigational

    Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).

    Synonyms: Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimer
  2. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease … [A1018] First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as _Galanthus nivalis_.

    Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    2-Hydroxy-5-({1-[(2-Naphthyloxy)Methyl]-3-Oxoprop-1-Enyl}Amino)Tyrosine

    go.drugbank.com/drugs/DB02511
    Experimental

    Synonyms: 2-Hydroxy-5-{[(2E)-1-(2-naphthyloxy)-4-oxo-2-buten-2-yl]amino}-L-tyrosine, 2-Hydroxy-5-({1-[(2-Naphthyloxy)Methyl]-3-Oxoprop-1-Enyl}Amino)Tyrosine
  4. Drug

    Perastine

    go.drugbank.com/drugs/DB20513
    Experimental

    Perastine is a small molecule drug. The usage of the INN stem '-astine' in the name indicates that Perastine is a antihistaminic. Perastine has a monoisotopic molecular weight of 295.19 Da.

    Synonyms: Perastine
  5. Drug

    {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum

    go.drugbank.com/drugs/DB03983
    Experimental

    Synonyms: {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum, (Molybdopterin-S,S)-dioxo-thio-molybdenum(V)
  6. Drug

    Tolterodine

    go.drugbank.com/drugs/DB01036
    ApprovedInvestigational

    Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

    Synonyms: (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Silodosin

    go.drugbank.com/drugs/DB06207
    ApprovedInvestigational

    a negative impact on the quality of life of patients. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder

    Categories: Drugs Used in Benign Prostatic Hypertrophy, Cytochrome P-450 SubstratesProducts: SILODOSINA EG, SILODOSIN AL 4 MG HKP
  8. Drug

    Livmoniplimab

    go.drugbank.com/drugs/DB18939
    Investigational

    Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination … With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).

    Synonyms: Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) (human monoclonal abbv-151 .gamma.4-chain), disulfide with human monoclonal abbv-151 .kappa.
  9. Drug

    Efmarodocokin alfa

    go.drugbank.com/drugs/DB16398
    Investigational

    Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).

    Synonyms: HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10>P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS,, INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN FC REGION (81-GLYCINE)), DIMER
  10. Drug

    Navafenterol

    go.drugbank.com/drugs/DB19195
    Investigational

    Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).

    Synonyms: -hydroxy-.alpha.-2-thienyl-, trans-4-((3-(5-((((2r)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-hydroxyethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)methylamino)cyclohexyl ester, Trans-4-((3-(5-((((2r)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-5- quinolinyl)ethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)(methyl)amino)cyclohexyl hydroxy(di-2-thienyl)acetateCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring