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Alglucosidase alfa
go.drugbank.com/drugs/DB01272ApprovedInvestigationalIt is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages of lysosomal glycogen.
Sodium sulfide
go.drugbank.com/drugs/DB11159ApprovedHowever the clinical significance and mechanism of action of sodium sulfide and replication of results across other studies are not yet fully determined. … Interestingly, sodium sulfide was shown to have some cardioprotective role against cardiac ischemia or reperfusion injury, as well as protect lungs against ventilator-induced lung injury [A27275].
Perflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalDuring echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Canagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalIt was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type
Mitiglinide
go.drugbank.com/drugs/DB01252InvestigationalIt may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Cefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedIt is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. … The advantage of using injectable antibiotics is not missing a dose that can allow partially resistant microbes to recover during missed doses.
Demecarium
go.drugbank.com/drugs/DB00944ApprovedCholinesterase inhibitors prolong the effect of acetylcholine, which is released at the neuroeffector junction of parasympathetic postganglion nerves, by inactivating the cholinesterases that break it
HNM01
go.drugbank.com/drugs/DB06531ExperimentalIt entered Phase 1 clinical trials for the treatment of HIV infections but was discontinued during this phase … The drug hNM01, a humanized monoclonal antibody developed by SRD Pharmaceuticals, Inc., targets the V(3) region of the HIV-1 envelope protein gp120, functioning as an HIV replication inhibitor.
Influenza A virus A/South Australia/55/2014 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB11001ApprovedWithdrawnVaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
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