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TTI-101
go.drugbank.com/drugs/DB17578InvestigationalSynonyms: Benzenesulfonamide, n-(1',2-dihydroxy(1,2'-binaphthalen)-4'-yl)-4-methoxy-, Stat3 inhibitor c188-9Atpenin A5
go.drugbank.com/drugs/DB04631ExperimentalSynonyms: 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinoneCategories: Heterocyclic Compounds, 1-RingOxfenicine
go.drugbank.com/drugs/DB04291ExperimentalOxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Synonyms: L-2-(p-hydroxyphenyl)glycine, (2S)-Amino(4-Hydroxyphenyl)Acetic AcidCategories: Carnitine O-Palmitoyltransferase, antagonists & inhibitorsThymoquinone
go.drugbank.com/drugs/DB16447InvestigationalThymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial.
Synonyms: 2-Isopropyl-5-methyl-p-benzoquinone, p-Cymene-2,5-dioneLunresertib
go.drugbank.com/drugs/DB19241InvestigationalSynonyms: (1S)-2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxamideNesolicaftor
go.drugbank.com/drugs/DB15239InvestigationalNesolicaftor (PTI-428) is under investigation in clinical trial NCT03258424 (Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background
Synonyms: N-(trans-3-(5-((R)-1-hydroxyethyl)-1,3,4-oxadiazol-2-yl)cyclobutyl)-3-phenylisoxazole-5-carboxamideN-Formylmethionine
go.drugbank.com/drugs/DB04464ExperimentalN-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA.
Synonyms: (2S)-2-(formylamino)-4-(methylthio)butanoic acid, L-N-FormylmethionineSB-218078
go.drugbank.com/drugs/DB17051ExperimentalSB-218078 is a specific inhibitor of CHK1.[A253117]
Synonyms: 9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2h)-dione, 9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2h)-dione, 9,10,11,12-tetrahydro-Telacebec
go.drugbank.com/drugs/DB17754InvestigationalSynonyms: 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine-3-carboxamide, Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl)phenyl)methyl)-Categories: Heterocyclic Compounds, 1-RingTAK-733
go.drugbank.com/drugs/DB12241InvestigationalTAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
Synonyms: 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, (R)-3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLUORO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO(2,3-D)PYRIMIDINE-4,7(3H,8H)-DIONECategories: Heterocyclic Compounds, 1-Ring