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Displaying results 3841 - 3850 of 10000 in total
  1. Drug

    Fresolimumab

    go.drugbank.com/drugs/DB12396
    Investigational

    Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis

  2. Drug

    Lumretuzumab

    go.drugbank.com/drugs/DB12683
    Investigational

    Lumretuzumab has been used in trials studying the treatment of Neoplasms, Breast Cancer, Squamous Non-Small Cell Lung Cancer, and Non-Squamous Non-Small Cell Lung Cancer.

  3. Drug

    Incyclinide

    go.drugbank.com/drugs/DB11647
    Investigational

    Incyclinide has been used in trials studying the treatment of HIV Infection, AIDS-related Kaposi Sarcoma, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.

  4. Drug

    Apricoxib

    go.drugbank.com/drugs/DB12378
    Investigational

    Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Sonolisib

    go.drugbank.com/drugs/DB12601
    Investigational

    Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others.

  6. Target

    Phosphoglycerate Kinases

    go.drugbank.com/bio_entities/BE0009688
    EnzymeHumans

    Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed:30323285, PubMed:7391028). Both L- and D- forms of purine and pyrimidine nuc...

    Synonyms: Cell migration-inducing gene 10 protein
  7. Target

    Sphingolipid delta(4)-desaturase DES1

    go.drugbank.com/bio_entities/BE0011584
    TargetHumans

    Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338). Catalyzes the equilibrium isomerization of retinols (By similar...

    Synonyms: Cell migration-inducing gene 15 protein
  8. Target

    Serine hydrolase RBBP9

    go.drugbank.com/bio_entities/BE0011987
    TargetHumans

    Serine hydrolase (Probable) (PubMed:32196348). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (PubMed:32196348). May negatively regulate basal or ...

    Synonyms: B5T-overexpressed gene protein
  9. Drug

    OCU400

    go.drugbank.com/drugs/DB18277
    Investigational

    OCU400 is a novel gene therapy comprising an adeno-associated viral vector expressing human nuclear hormone receptor subfamily 2 group E member 3 (hNR2E3).

  10. Drug

    Etalocib

    go.drugbank.com/drugs/DB12850
    Investigational

    Etalocib has been used in trials studying the treatment of Pancreatic Cancer, Carcinoma, Non-Small-Cell Lung, and Unspecified Adult Solid Tumor, Protocol Specific.