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PRTX-100
go.drugbank.com/drugs/DB05947InvestigationalThese binding interactions enable the compound to modulate the function of these cells and restore the balance of the immune system. … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases
Lynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of norethisterone.
Categories: Sex Hormones and Modulators of the Genital SystemSodium tetradecyl sulfate
go.drugbank.com/drugs/DB00464ApprovedAn anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Synonyms: Tetradecyl sulfate de sodiumSPP 301
go.drugbank.com/drugs/DB05290InvestigationalThis study was designed to evaluate whether avosentan influences the pharmacokinetics of steroid oral contraceptives. … SPP301 (Avosentan) is a potent and highly selective ET[A] receptor blocker and is clinically investigated in diabetic nephropathy.
Incadronic acid
go.drugbank.com/drugs/DB06255ExperimentalAlong with being investigated to treat hypercalcemia of malignancy,[A202862] it has also been investigated in the treatment of myeloma, leukemia, and other cancers. … [A14426,A14431,A14427,A202769] Incadronic acid was first described in the literature in 1991.[A202289]
Ginsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalGinsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. … Because ginsenosides appear to affect multiple pathways, their effects are complex and difficult to isolate. Rg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng).
Pomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalPomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Betaxolol
go.drugbank.com/drugs/DB00195ApprovedInvestigationalA cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Ritanserin
go.drugbank.com/drugs/DB12693InvestigationalRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome