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Papain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnWhile it has been used for the treatment of inflammation and pain via topical administration, papain has also shown to have anthelmintic and tooth-whitening properties. … The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
Nomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Synonyms: 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dioneCategories: Hormonal Contraceptives for Systemic UseUCB-1184197
go.drugbank.com/drugs/DB05092InvestigationalCDP323 was originally developed by the British biopharmaceutical company Celltech plc. (now UCB S.A.) and is a putative new drug for oral treatment of multiple sclerosis.
α-Methylacetylfentanyl
go.drugbank.com/drugs/DB01532ExperimentalIllicitanhydride for the production of chemical propionic anhydride in the synthesis. … It was categorized under the Schedule I in the US and it was illegally sold in early 1980. α-Methylacetylfentanyl synthesis process is very similar to α-methylfentanyl with the substitution of the acetic
Canis lupus familiaris dander
go.drugbank.com/drugs/DB11018ApprovedCanis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.
Mixtures: Animal Allergens, UF Dog Hair-Dander Canis sppTrofinetide
go.drugbank.com/drugs/DB06045Approved[A258438] Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive … , making trofinetide the first and only treatment approved for Rett syndrome in the European Union.
Mirdametinib
go.drugbank.com/drugs/DB07101ApprovedInvestigationalOn February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1). … [L52485] NF1 is an autosomal-dominant genetic condition caused by loss-of-function variants in the _NF1_ tumour suppressor gene,[A265065,A265070] leading to neurofibromin dysfunction and aberrant activation
ILY101
go.drugbank.com/drugs/DB05059InvestigationalILY101 is a metal-free, non-absorbed polymeric drug designed for the selective binding and removal of phosphate anions from the gastrointestinal tract. … ILY101 is being developed for the treatment of hyperphosphatemia in CKD patients on dialysis and works by reducing the systemic absorption of dietary phosphate.
V590
go.drugbank.com/drugs/DB16437ExperimentalBy teaming up with IAVI, Merk developed a vaccine that does not require freezing, and only requires one dose[L30583]. … Merck is currently underway to begin Phase I trials for the vaccine through intramuscular administration (NCT04569786).
Eniluracil
go.drugbank.com/drugs/DB03516InvestigationalEniluracil has received Orphan Drug status from the FDA for the treatment of hepatocellular cancer in combination with fluoropyrimidines (including 5-FU). … Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available.