Nomegestrol acetate

DB13981ApprovedSmall molecule

Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.

Chemical structure of Nomegestrol acetate
Mechanism
Curator reviewed
Formula / weight
C23H30O4 · 370.489 g/mol (avg)
First approval
European Union, 2016
Code names
ORG 10486-0 · TX-066
Brand names
  • Zoely

Resolves to

Compound
UNII83J78V5W05CAS58652-20-3ChEMBLCHEMBL1476022ChEBI135564KEGGD08281
Clinical / RWD
RxNorm53744
Structure
InChIKeyIIVBFTNIGYRNQY-YQLZSBIMSA-NSMILES[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3C(C)=C[C@@]21[H]
Targets
P06401PGRP03372ESR1

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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544Drug interactionsStructured to mechanism, not free text
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11Clinical trialsPhase, status and sponsor resolved per trial
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4Structured indicationsCondition, population, route and combination as fields, not prose
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24Marketed productsAcross 5 countries and 10 labellers
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Nomegestrol acetate, and which of those have an active Phase 3 trial?

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