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Displaying results 3871 - 3880 of 10000 in total
  1. Drug

    Metelimumab

    go.drugbank.com/drugs/DB18695
    Experimental

    Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.

    Synonyms: Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with human monoclonal cat-192 .kappa.-chain, dimer, Human anti-transforming growth factor beta 1 monoclonal antibody
  2. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment

    Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Bromhexine

    go.drugbank.com/drugs/DB09019
    ApprovedInvestigational

    Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. … It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries.

    Mixtures: GLICERTOX N F, PENAMOX MSynonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine
  4. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Mixtures: TOBRAMICINA E DESAMETASONE EG, NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADETCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  5. Drug

    Glimepiride

    go.drugbank.com/drugs/DB00222
    ApprovedInvestigational

    Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular … First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control.

    Mixtures: AMARYL®M 4 MG/ 1000 MG, AMARYL M 4 MG/1000 MG FİLM KAPLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  6. Drug

    (E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER

    go.drugbank.com/drugs/DB04613
    Experimental

    Synonyms: (E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER
  7. Drug

    (4R)-limonene 1α,2α-epoxide

    go.drugbank.com/drugs/DB02924
    Experimental

    Synonyms: 1α,2α-epoxy-4βH-p-menth-8-ene, (1S,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptane
  8. Drug

    Tocilizumab

    go.drugbank.com/drugs/DB06273
    ApprovedInvestigational

    [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. … [L44483] Tocilizumab-bavi, a biosimilar drug, was approved by the FDA in September 2023.[L48385].

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ACTEMRA 80 MG/4 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADET, ACTEMRA 80 MG/4 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET
  9. Drug

    PXL-770 free acid anhydrous

    go.drugbank.com/drugs/DB17615
    Experimental

    Synonyms: 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo- 5-phenyl-6,7-dihydrothieno(2, 3-b)pyridin-4-olateCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Tepilamide fumarate

    go.drugbank.com/drugs/DB18804
    Investigational

    Synonyms: (n,n-diethylcarbamoyl)methyl methyl (2e)-but-2-ene-1,4-dioate, 2-butenedioic acid (2e)-, 1-(2-(diethylamino)-2-oxoethyl) 4-methyl ester