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Triazolam
go.drugbank.com/drugs/DB00897ApprovedInvestigationalWithdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. … Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Pomaglumetad methionil
go.drugbank.com/drugs/DB05096InvestigationalFor LY2140023, the active substance, LY404039, is thought to work by reducing the presynaptic release of another neurotransmitter, glutamate, in brain regions where mGlu2/3 receptors are expressed. … LY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039.
Lonidamine
go.drugbank.com/drugs/DB06266InvestigationalIn such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs. … Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
OPC-14523
go.drugbank.com/drugs/DB05422ExperimentalOPC-14523 is an antidepressant drug developed by Otsuka America Pharmaceutical.
Adenosine 5'-[gamma-thio]triphosphate
go.drugbank.com/drugs/DB02930ExperimentalA nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Categories: Compounds used in a research, industrial, or household settingOsemozotan
go.drugbank.com/drugs/DB05339ExperimentalMN-305 is a novel, potent and highly selective serotonin 5-HT1A receptor agonist under development by MediciNova for the treatment of anxiety disorders beginning with Generalized Anxiety Disorder (GAD)
Corticorelin
go.drugbank.com/drugs/DB05394InvestigationalCorticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … It is a type of neurohormone, also called hCRF.
AdPEDF
go.drugbank.com/drugs/DB05138ExperimentalIt has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors … AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD).
Trehalose-6-Phosphate
go.drugbank.com/drugs/DB02430ExperimentalCategories: Compounds used in a research, industrial, or household settingSucralose
go.drugbank.com/drugs/DB15049InvestigationalSucralose is an artificial sweetener used as a sugar substitute.
Categories: Compounds used in a research, industrial, or household setting