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Eph receptors
go.drugbank.com/bio_entities/BE0028186TargetHumansForward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. … Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.
Synonyms: SEK, Tyrosine-protein kinase receptor SEKFurazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approvedA nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Categories: Genito Urinary System and Sex HormonesDapoxetine
go.drugbank.com/drugs/DB04884InvestigationalIn a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.
Categories: Genito Urinary System and Sex HormonesSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalSodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acet...
Mixtures: SMOFKABIVEN® PERIFERICO EMULSION PARA INFUSIONHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 1...
Categories: Sex Hormones and InsulinsProducts: HEM-EASY RELIEF Herbal Anti-Itch MAXIMUM ITCH RELIEFParamethasone
go.drugbank.com/drugs/DB01384ExperimentalA glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-reta...
Categories: Sex Hormones and InsulinsCyclin-dependent kinases
go.drugbank.com/bio_entities/BE0010231TargetHumansCan phosphorylate CCNY at 'Ser-336' (in vitro) … Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity)
Synonyms: Mediator complex subunit CDK8, Tat-associated kinase complex catalytic subunitPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigationalPembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotyp...