Search

Displaying results 3881 - 3890 of 10000 in total
  1. Drug

    VP025

    go.drugbank.com/drugs/DB05133
    Experimental

    It is considered to be a systemic anti-inflammatory and neuroprotective agent. … It is being developed to target the chronic inflammation within the central nervous system that is associated with a number of neurological diseases, including Alzheimer’s disease, Parkinson’s disease,

  2. Drug

    DTS-201

    go.drugbank.com/drugs/DB06071
    Experimental

    DTS-201 is a prodrug of doxorubicin, a widely used anti-cancer drug that Diatos intends to develop for the treatment of various solid tumors. It is activated in the tumor environment.

  3. Drug

    Pradefovir mesylate

    go.drugbank.com/drugs/DB05478
    Investigational

    Pradefovir is activated through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver. … The novel prodrug is highly stable in both plasma and tissues and demonstrated potent preclinical and clinical anti-HBV activity.

  4. Drug

    Dodecyldimethylamine N-oxide

    go.drugbank.com/drugs/DB04147
    Experimental

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N-Dimethyldodecylamine oxide, Dimethyldodecylamine N-oxide
  5. Drug

    Bimakalim

    go.drugbank.com/drugs/DB19948
    Experimental

    Bimakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive. … Bimakalim has a monoisotopic molecular weight of 278.11 Da.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Indecainide

    go.drugbank.com/drugs/DB00192
    Approved

    Indecainide is a rarely used antidysrhythmic. … Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics

  7. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation.

  8. Drug

    Lufenuron

    go.drugbank.com/drugs/DB11424
    ExperimentalVet approved

    Lufenuron is used in veterinary for the control of flea.

    Synonyms: N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamideCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    SSR-126517E

    go.drugbank.com/drugs/DB05362
    Experimental

    SSR-126517E is a second generation synthetic pentasaccharide that binds antithrombin with such high affinity that it assumes a plasma half-life of 80 hours.

  10. Drug

    CYT007-TNFQb

    go.drugbank.com/drugs/DB05758
    Experimental

    CYT007-TNFQb is an active immunization therapy that aims at providing a novel treatment to people suffering from RA or psoriasis. … The vaccine should allow for administration of low amounts of drug to individual patients (in the microgram range) and for convenient dosing schedules.