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Berahyaluronidase alfa
go.drugbank.com/drugs/DB22790ApprovedInvestigationalpreviously only available via intravenous administration, including melanoma, non-small cell lung cancer, and urothelial cancer. … This combination was approved by the US FDA in September 2025 and is indicated for various solid tumors in adults and pediatric patients 12 years and older, offering a subcutaneous option for indications
Ichthammol
go.drugbank.com/drugs/DB11341ApprovedIt is available in OTC products as an active ingredient for the treatment of skin disorders such as eczema, psoriasis and boils as it is thought to exhibit anti-inflammatory, antibacterial and antimycotic … It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed by sulfonation and neutralization.
Magnesium gluconate
go.drugbank.com/drugs/DB13749ApprovedWithdrawnMagnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids … Although magnesium is available in the form of sulphates, lactate, hydroxide, oxide and chloride, only magnesium gluconate is recommended for magnesium supplementation as it appears to be better absorbed
Tecovirimat
go.drugbank.com/drugs/DB12020ApprovedInvestigational[L40154] Tecovirimat is available as both oral and intravenous formulations.[L41835] … [L3626, L3614] Tecovirimat was later approved by Health Canada in December 2021,[L39397] followed by the approval from the European Commission in January 2022.
Menadione
go.drugbank.com/drugs/DB00170ApprovedNutraceuticalA synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Eslicarbazepine acetate
go.drugbank.com/drugs/DB09119ApprovedInvestigationalIt is available in 200, 400, 600, or 800mg tablets that are taken once daily, with or without food. … Eslicarbazepine's mechanism of action is not well understood, but it is known that it does exert anticonvulsant activity by inhibiting repeated neuronal firing and stabilizing the inactivated state of
Apadenoson
go.drugbank.com/drugs/DB05009InvestigationalIt is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Diiodohydroxyquinoline
go.drugbank.com/drugs/DB09115ApprovedIodoquinol is not currently available in any FDA-approved products.
Egg phospholipids
go.drugbank.com/drugs/DB14233ApprovedWithdrawnEgg phospholipids are available as an intravenous fat emulsion indicated as a source of calories for patients requiring parenteral nutrition.
Tenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalTenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase