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Displaying results 381 - 390 of 10000 in total
  1. Drug

    Futibatinib

    go.drugbank.com/drugs/DB15149
    ApprovedInvestigational

    Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and … FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl)-2-propen-1-one
  2. Drug

    Stallimycin

    go.drugbank.com/drugs/DB20261
    Experimental

    Stallimycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Stallimycin is a antibiotic, produced by Streptomyces strain. … Stallimycin has a monoisotopic molecular weight of 481.22 Da.

    Synonyms: Distamycin a
  3. Drug

    Basifungin

    go.drugbank.com/drugs/DB14058
    Experimental

    Basifungin, also known as _aureuobacidin A_, is a phosphorylceramide synthase inhibitor [L2960], [A33381].

    Synonyms: Aureobasidin A
  4. Drug

    Mibolerone

    go.drugbank.com/drugs/DB11429
    ExperimentalVet approved

    Mibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone.

    Synonyms: 17-beta-Hydroxy-7-alpha,17-dimethylestr-4-en-3-one, (7α,17β)-17-hydroxy-7,17-dimethylestr-4-en-3-oneCategories: Estranes
  5. Drug

    Streptolydigin

    go.drugbank.com/drugs/DB04785
    Experimental

    Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

    Synonyms: Afragilimycin A
  6. Drug

    Cefaloridine

    go.drugbank.com/drugs/DB09008
    ApprovedWithdrawn

    Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: ((6R,7R)-1-((2-CARBOXY-8-OXO-7-(2-(2-THIENYL)ACETAMIDO)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)PYRIDINIUM HYDROXIDE, INNER SALT, PYRIDINIUM, 1-((2-CARBOXY-8-OXO-7-((2-THIENYLACETYL)AMINO)-5-THIA-1-AZABICYCLO(4.2.0)-OCT-2-EN-3-YL)METHYL)-, HYDROXIDE, INNER SALT, (6R-TRANS)-
  7. Drug

    Hexanoyl-CoA

    go.drugbank.com/drugs/DB02563
    Experimental

    Synonyms: n-hexanoyl-coenzyme A, S-Hexanoyl-coenzym-ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  8. Drug

    Lixadesiran

    go.drugbank.com/drugs/DB17295
    Experimental

    Synonyms: Rna, (a-c-a-u-c-a-u-c-a-g-a-c-c-a-g-g-c-a-c-c-a-g-a-c-c), complex with rna (g-g-u-c-u-g-g-u-g-c-c-u-g-g-u-c-u-g-a-u-g-a-u-g-u) (1:1)
  9. Drug

    N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)heptadec-3-en-1-yl]acetamide

    go.drugbank.com/drugs/DB06960
    Experimental

    Synonyms: N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)heptadec-3-en-1-yl]acetamide
  10. Drug

    Acetoacetyl-CoA

    go.drugbank.com/drugs/DB03059
    Experimental

    Synonyms: S-Acetoacetyl-coenzym A, S-acetoacetyl-coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring