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AT3022
go.drugbank.com/drugs/DB05172ExperimentalAT3022, the Altea Therapeutics’s fentanyl citrate transdermal patch designed to provide safe and rapid management of moderate to severe chronic pain.
HY10275
go.drugbank.com/drugs/DB05079ExperimentalHY10275 was rationally designed to "let you sleep" rather than depress the entire brain to "make you sleep." … HY10275 is highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ability to fall asleep and stay asleep.
SP1049C
go.drugbank.com/drugs/DB04978ExperimentalPreliminary data, in its first clinically tested indication, shows that SP1049C is active in Stage IV non-resectable adenocarcinoma of the esophagus. … [A260416] It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review.
Poliglusam
go.drugbank.com/drugs/DB11234ApprovedInvestigationalNaturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase … In comparison, commercial poliglusam is derived from deacetylation of chitin contained in the shells of various sea crustaceans such as shrimps [L999].
Natural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalNK Cells express features of innate immune responses, and respond to all molecules that appear to be foreign to the body. … Expansion involves the use of feeder cell line systems or bioreactors to enhance the number of NK cells with desired cytotoxicity.
PRO 2000
go.drugbank.com/drugs/DB05385InvestigationalThis medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people. … It is being studied for the prevention of HIV infection and other sexually transmitted diseases.
Abivertinib
go.drugbank.com/drugs/DB15327InvestigationalThe study is expected to be completed in March 2021.[L17398] … [L17388] Abivertinib's potential to depress cytokine production has led to its investigation in the treatment of hospitalized patients with moderate-to-severe COVID-19.
Bismuth subcitrate potassium
go.drugbank.com/drugs/DB09275ApprovedInvestigationalA bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Products: DE NOL, DE-NOL 300 MG TABLET, 60 ADETAnti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356InvestigationalFrom there, the chicken antibodies are harvested from the egg yolks of the eggs laid by these chickens and formulated into the nasal drops that can be administered. … Anti-SARS-CoV-2 IgY are chicken egg antibodies to SARS-CoV-2 which have the potential to provide temporary protection against the virus when administered as intranasal drops.
ZYC300
go.drugbank.com/drugs/DB04986InvestigationalIt is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.