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Displaying results 3911 - 3920 of 10000 in total
  1. Target

    Serine hydrolase RBBP9

    go.drugbank.com/bio_entities/BE0011987
    TargetHumans

    Serine hydrolase (Probable) (PubMed:32196348). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (PubMed:32196348). May negatively regulate basal or ...

    Synonyms: B5T-overexpressed gene protein
  2. Drug

    Adomiparin

    go.drugbank.com/drugs/DB06005
    Investigational

  3. Drug

    EVT 302

    go.drugbank.com/drugs/DB06057
    Investigational

    EVT 302 is an orally active, potent, highly selective and reversible inhibitor of MAO-B. It is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Linifanib

    go.drugbank.com/drugs/DB06080
    Investigational

    Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-3-(2-FLUORO-5-METHYLPHENYL)UREA, UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)-
  5. Drug

    APD668

    go.drugbank.com/drugs/DB05166
    Experimental

    APD668 is a novel, highly potent and orally active glucose-dependent insulinotropic receptor (GDIR) agonist intended to more efficiently stimulate insulin release by beta cells in response to elevated

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Berzosertib

    go.drugbank.com/drugs/DB11794
    Investigational

    Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    QR-1123

    go.drugbank.com/drugs/DB17869
    Investigational

    QR-1123 is a first-in-class investigational RNA-based oligonucleotide designed to treat autosomal dominant retinitis pigmentosa due to the P23H mutation in the rhodopsin (_RHO_) gene.[L46782]

  8. Drug

    Tesidolumab

    go.drugbank.com/drugs/DB11926
    Investigational

    Tesidolumab has been used in trials studying the treatment of Geographic Atrophy, Non-infectious Panuveitis, Exudative Macular Degeneration, Non-infectious Posterior Uveitis, and Age-related Macular Degeneration

  9. Drug

    Brivanib

    go.drugbank.com/drugs/DB11958
    Investigational

    Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Patritumab

    go.drugbank.com/drugs/DB12090
    Investigational

    Patritumab has been used in trials studying the treatment of LUNG CANCER, Solid Tumors, Neoplasms by Site, Head and Neck Neoplasms, and Non-small Cell Lung Cancer, among others.