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Displaying results 3911 - 3920 of 10000 in total
  1. Drug

    PS386113

    go.drugbank.com/drugs/DB05211
    Experimental

    Little information has been released about PS386113. … PS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders. It is being developed by Schering-Plough and Pharmacopeia.

  2. Target

    T-cell surface glycoprotein CD3

    go.drugbank.com/bio_entities/BE0010202
    TargetHumans

    In addition to its role as a TCR coreceptor, it serves as a receptor for ITPRIPL1 (PubMed:38614099). … Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G

    Synonyms: T-cell receptor T3 delta chain, T-cell receptor T3 zeta chain
  3. Drug

    Tabalumab

    go.drugbank.com/drugs/DB11657
    Investigational

    Tabalumab has been used in trials studying the treatment of Autoimmune Disease, Rheumatoid Arthritis, Kidney Failure, Chronic, Connective Tissue Disease, and Systemic Lupus Erythematosus, among others.

    Categories: B-Cell Activating Factor, antagonists & inhibitors
  4. Drug

    Eprenetapopt

    go.drugbank.com/drugs/DB11684
    Investigational

    Eprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.

    Synonyms: 1-Azabicyclo(2.2.2)octan-3-one, 2-(hydroxymethyl)-2-(methoxymethyl)-, 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
  5. Drug

    Astodrimer

    go.drugbank.com/drugs/DB11854
    Investigational

    Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Vatiquinone

    go.drugbank.com/drugs/DB11917
    Investigational

    Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.

  7. Drug

    Sapitinib

    go.drugbank.com/drugs/DB12183
    Investigational

    Sapitinib has been used in trials studying the treatment and basic science of Neoplasms, Breast Cancer, Breast Neoplasms, Metastatic Cancer, and Metastatic Breast Cancer, among others.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Polmacoxib

    go.drugbank.com/drugs/DB12399
    Investigational

    Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of

    Categories: COX-2 Inhibitors, Heterocyclic Compounds, 1-Ring
  9. Drug

    Theanine

    go.drugbank.com/drugs/DB12444
    Investigational

    Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).

    Synonyms: N(5)-ethyl-L-glutamine, N-ethyl-L-glutamine
  10. Drug

    Ditiocarb

    go.drugbank.com/drugs/DB02520
    Investigational

    A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

    Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors