Polmacoxib

DB12399InvestigationalSmall molecule

Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.

Chemical structure of Polmacoxib
Mechanism
Curator reviewed
Formula / weight
C18H16FNO4S · 361.39 g/mol (avg)
Code names
CG-100649

Resolves to

Compound
UNIIIJ34D6YPAOCAS301692-76-2ChEMBLCHEMBL166863PubChem9841854
Clinical / RWD
ATCM01AH07
Structure
InChIKeyIJWPAFMIFNSIGD-UHFFFAOYSA-NSMILESCC1(C)OC(=C(C1=O)C1=CC=CC(F)=C1)C1=CC=C(C=C1)S(N)(=O)=O
Targets
P00918CA2P00915CA1P35354PTGS2

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
686Drug interactionsStructured to mechanism, not free text
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6Clinical trialsPhase, status and sponsor resolved per trial
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1ATC codeIncluding every combination product, plus 11 drug categories
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Polmacoxib, and which of those have an active Phase 3 trial?

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