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Sulfadoxine
go.drugbank.com/drugs/DB01299ApprovedInvestigationalWithdrawnA long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Digitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnIt has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
OBE101
go.drugbank.com/drugs/DB05080ExperimentalOBE101 is a new weight loss drug developed by Obecure Ltd. It is a new formulation that is based on the vertigo medication, Betahistine.
LS11
go.drugbank.com/drugs/DB05918InvestigationalIt is used to treat many kinds of cancers. … After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death.
Selisistat
go.drugbank.com/drugs/DB13978InvestigationalSelective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3 … Enhances p53 acetylation in response to DNA damaging agents.
OMS-103HP
go.drugbank.com/drugs/DB05303InvestigationalOMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Androstenediol
go.drugbank.com/drugs/DB01524ExperimentalIllicitAndrostenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group … to a 3-keto group (3-hydroxysteroid dehydrogenases).
Foscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.