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Displaying results 3931 - 3940 of 10000 in total
  1. Drug

    Arbaclofen

    go.drugbank.com/drugs/DB08891
    Investigational

    It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind … It has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord injury.

    Synonyms: (R)-4-amino-3-(4-chlorophenyl)butan­oic acid, (R)-Baclofen
  2. Drug

    Rivanicline

    go.drugbank.com/drugs/DB05855
    Experimental

    It has subsequently been developed as a potential anti-inflammatory treatment for ulcerative colitis. … It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine, (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine
  3. Target

    Diacylglycerol O-acyltransferase 1

    go.drugbank.com/bio_entities/BE0012021
    TargetHumans

    Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates (PubMed:16214399, PubMed:18768481, PubMed:28420705, PubMed:32433610, PubMed:32433611, PubMed:9756920). H...

    Synonyms: ACAT-related gene product 1
  4. Target

    P2Y purinoceptor 12

    go.drugbank.com/bio_entities/BE0000110
    TargetHumans

    Receptor for ADP and ATP coupled to G proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation

    Synonyms: ADP-glucose receptor, P2Y12 platelet ADP receptorFunction: G protein-coupled adenosine receptor activity
  5. Drug

    Omecamtiv Mecarbil

    go.drugbank.com/drugs/DB11816
    Investigational

    Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among

  6. Drug

    Dipropyl-4-hydroxytryptamine

    go.drugbank.com/drugs/DB13990
    Experimental

    This agent and its properties haven't been fully elucidated. … Dipropyl-4-hydroxytryptamine is the 4-hydroxyl analog of dipropyltryptamine (DPT). Dipropyl-4-hydroxytryptamine was first synthesized by Alexander Shulgin.

    Synonyms: 4-Hydroxy-N,N-dipropyltryptamine, 3-[2-(Dipropylamino)ethyl]-1H-indol-4-ol
  7. Drug

    Creatinolfosfate

    go.drugbank.com/drugs/DB13071
    Investigational

    COP has been investigated for the treatment of Diabetic Retinopathy. … COP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease.

  8. Drug

    Dusigitumab

    go.drugbank.com/drugs/DB12363
    Investigational

    Dusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic

  9. Drug

    BIIB015

    go.drugbank.com/drugs/DB06304
    Investigational

    BIIB015 is a humanized, IgG1 [immunoglobulin G 1], DM4-Conjugated, anti-cripto, monoclonal antibody. It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.

  10. Drug

    AAV8-RK-RetGC

    go.drugbank.com/drugs/DB32389
    Experimental

    AAV8-RK-RetGC is an adeno-associated virus (AAV) viral vector platform with a serotype 8 capsid with a complementary DNA (cDNA) of the human GUCY2D gene encoding RetGC.