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Displaying results 3931 - 3940 of 10000 in total
  1. Drug

    Rivastigmine

    go.drugbank.com/drugs/DB00989
    ApprovedInvestigational

    Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.

    Synonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamateCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Biperiden

    go.drugbank.com/drugs/DB00810
    ApprovedInvestigationalWithdrawn

    A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism.

    Synonyms: 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol, alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanolCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 Inhibitors
  3. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. … There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304].

    Mixtures: Skin Shield, Numb SkinProducts: Antiseptic Skin Cream - 1mg/g, Finipil 4 Men Only
  4. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    Nicotine is also important medically because of its presence in tobacco smoke.

    Synonyms: (S)-3-(1-methylpyrrolidin-2-yl)pyridine, (S)-3-(N-methylpyrrolidin-2-yl)pyridineCategories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependence
  5. Drug

    Abatacept

    go.drugbank.com/drugs/DB01281
    ApprovedInvestigational

    Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human … [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each

    Categories: Selective T Cell Costimulation ModulatorProducts: ORENCIA SUBKUTAN 125 MG ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR 4 ADET, ORENCIA® SOLUCION INYECTABLE PARA ADMINISTRACION SUBCUTÁNEA 125 MG/ML
  6. Drug

    Darbepoetin alfa

    go.drugbank.com/drugs/DB00012
    ApprovedInvestigational

    Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.

    Products: ARANESP 60 MCG KULLANIMA HAZIR DOLU ENJEKTOR ICINDE ENJEKSIYONLUK COZELTI, 4 ADET, ARANESP 500UG ILO IN FER
  7. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring. … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile, fosfomycin has largely become a first-line therapeutic option for the treatment of uncomplicated

    Synonyms: L-cis-1,2-epoxypropylphosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acidProducts: Fosfomycin Infectopharm 40 mg/ml Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, SOLUFOS® 500 MG
  8. Drug

    European pilchard

    go.drugbank.com/drugs/DB10622
    Approved

    European pilchard allergenic extract is used in allergenic testing.

    Synonyms: European pilchard
  9. Drug

    Erdafitinib

    go.drugbank.com/drugs/DB12147
    ApprovedInvestigational

    [L5956, L5959] Considering urothelial cancer is statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a much-needed new option in the ever-expanding therapeutic … tool kit to treat such a prevalent medical condition.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: BALVERSA 4 MG FİLM KAPLI TABLET, 56 ADET, BALVERSA 4 MG FİLM KAPLI TABLET, 28 ADET
  10. Drug

    Glycopyrronium

    go.drugbank.com/drugs/DB00986
    ApprovedInvestigationalVet approved

    [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.

    Mixtures: TRIMBOW PRESSURISED INHALATION SOLUTION 100/6/12.5 μg PER ACTUATION, TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 Substrates