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Displaying results 3941 - 3950 of 10000 in total
  1. Drug

    fb-PMT

    go.drugbank.com/drugs/DB17394
    Investigational

    Synonyms: 2-(4-(4-((1-(107- (4-(fluorophenyl)methoxy)-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5- diiodophenoxy)-3,5-diiodophenyl)acetic acid, O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid)polyethylene glycol
  2. Drug

    Trabectedin

    go.drugbank.com/drugs/DB05109
    ApprovedInvestigational

    Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically. … Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: TRABECTEDINA EG, Trabectedin TEVA 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  3. Drug

    Ulodesine

    go.drugbank.com/drugs/DB12353
    Investigational

    Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4H-PYRROLO(3,2-D)PYRIMIDIN-4-ONE, 1,5-DIHYDRO-7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)-1-PYRROLIDINYL)METHYL)-, 7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL)METHYL(-1,5-DIHYDRO-4H-PYRROLO(3,2-D)PYRIMIDIN-4-ONE
  4. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39076] On the available products, ibuprofen is administered as a racemic mixture. … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.

    Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-X
  5. Drug

    Dibromothymoquinone

    go.drugbank.com/drugs/DB04646
    Experimental

    At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. … At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]

    Synonyms: 2,5-dibromo-3-methyl-6-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 2,5-dibromo-3-methyl-6-(1-methylethyl)cyclohexa-2,5-diene-1,4-dione
  6. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Mixtures: TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 30 ADET, TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 90 ADETCategories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  7. Drug

    Lidocaine

    go.drugbank.com/drugs/DB00281
    ApprovedInvestigationalVet approved

    As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. … Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis.

    Synonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide, 2-(Diethylamino)-2',6'-acetoxylidideInternational brands: L-Caine, Lidoject-1
  8. Drug

    Dovramilast

    go.drugbank.com/drugs/DB16242
    Investigational

    Dovramilast is under investigation in clinical trial NCT01300208 (To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid

    Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 InhibitorsSynonyms: Cyclopropanecarboxamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-3-oxo-1H-isoindol-4-yl]-, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2- (methanesulfonyl)ethyl]-3-oxo-2,3-dihydro-1H-isoindol- 4-yl}cyclopropanecarboxamide
  9. Drug

    Celastrol

    go.drugbank.com/drugs/DB18736
    Experimental

    Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_.[L50567]

    Synonyms: 24-nor-d:a-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha.,14.beta.,20.alpha.)-
  10. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.

    Mixtures: Me NaPhos MB Hyo 1, Uro-LSynonyms: L-Hyoscyamine, L-Tropine tropate