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Arbaclofen
go.drugbank.com/drugs/DB08891InvestigationalIt has also been investigated as a treatment for spasticity due to multiple sclerosis and spinal cord injury. … It is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind
Brotizolam
go.drugbank.com/drugs/DB09017ApprovedWithdrawnBrotizolam has similar effects to short-acting benzodiazepines such as triazolam. Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia.
Products: BROTIZOLAM DOC GENERICISuccinobucol
go.drugbank.com/drugs/DB05399InvestigationalAGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary
EDP1815
go.drugbank.com/drugs/DB16486InvestigationalEDP1815, was investigated in several clinical trials (NCT05066373, NCT05439941, NCT05682222, NCT03733353, NCT04603027, NCT04488575, NCT05121480, NCT04393246) to evaluate its safety and efficacy in conditions
Motexafin lutetium
go.drugbank.com/drugs/DB05296InvestigationalIt belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Picoplatin
go.drugbank.com/drugs/DB04874InvestigationalIt causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription.
AEG35156
go.drugbank.com/drugs/DB06184InvestigationalThis agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. … XIAP interferes with both the intrinsic and extrinsic program-death signaling pathways, which may render tumor cells resistant to apoptosis.
VT-111
go.drugbank.com/drugs/DB05646InvestigationalVT-111 is a 55 kDa secreted glycoprotein belonging to a superfamily of proteins called SERPINS, which share a general structure and mechanism for proteinase inhibition.
Bambuterol
go.drugbank.com/drugs/DB01408InvestigationalBambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Categories: Agents to Treat Airway DiseaseAD 337
go.drugbank.com/drugs/DB05725InvestigationalThe drug was created by Sosei pharmaceuticals to treat Fibromyalgia in female patients. … AD 337 was under investigation in clinical trial NCT00377039 (A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia).