Brotizolam

DB09017ApprovedWithdrawnSmall molecule

Brotizolam is a benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia. Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog.

Chemical structure of Brotizolam
Mechanism
Curator reviewed
Primary indication
Brotizolam is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia.Curator reviewed · 1 structured indication
Formula / weight
C15H10BrClN4S · 393.689 g/mol (avg)
Code names
SID144207150 · WE-941 · WE 941-BS

Resolves to

Compound
UNII5XZM1R3DKFCAS57801-81-7ChEMBLCHEMBL32479ChEBI31308PubChem2451KEGGD01744
Clinical / RWD
RxNorm19790ATCN05CD09
Structure
InChIKeyUMSGKTJDUHERQW-UHFFFAOYSA-NSMILESCC1=NN=C2CN=C(C3=C(SC(Br)=C3)N12)C1=CC=CC=C1Cl

What you can answer from here — as of March 06, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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804Drug interactionsStructured to mechanism, not free text
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5Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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8ContraindicationsEach with its own population and attribute set
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36Marketed productsAcross 3 countries and 16 labellers
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1ATC codeIncluding every combination product, plus 10 drug categories
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6+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Brotizolam, and which companies have late-stage candidates in those indications?

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